Genetic imprinting disorders

Silver-Russell syndrome is a rare genetic disorder characterized by growth delay, low birth weight, and overall small size. This syndrome is often associated with changes in genes on chromosomes 11 and 7, leading to developmental delays both cognitively and physically. Common symptoms include body asymmetry (such as limb length discrepancy), feeding difficulties, and facial abnormalities like a broad forehead or a prominent nose.

Temple syndrome is a rare genetic disorder characterized by growth delay, microcephaly (small head size), dental development issues, and distinctive facial features such as a broad forehead and a round nose. Individuals with this syndrome may experience developmental delays in cognitive functions, physical growth issues, and sometimes hearing problems. It is caused by genetic changes, often linked to alterations in chromosomes, such as chromosome 16.

Transient neonatal diabetes is a temporary condition that occurs immediately after birth, where a newborn experiences elevated blood sugar levels due to a malfunction in insulin secretion. This disorder is often caused by an issue with the pancreas's ability to regulate insulin. In most cases, transient diabetes resolves on its own within the first few weeks of life after blood sugar levels are normalized, but in some instances, it may persist longer and require treatment.